Genetic characterisation of an influenza A virus of unusual subtype (H1N7) isolated from pigs in England
Identifieur interne : 001B82 ( Main/Exploration ); précédent : 001B81; suivant : 001B83Genetic characterisation of an influenza A virus of unusual subtype (H1N7) isolated from pigs in England
Auteurs : I. H. Brown ; M. L. Hill ; P. A. Harris ; D. J. Alexander ; J. W. MccauleySource :
- Archives of Virology [ 0304-8608 ] ; 1997-05-01.
Abstract
Summary: An H1N7 influenza A virus, isolated from pigs in England in 1992, was examined genetically to determine the characteristics and probable origin of the eight gene segments. Six of the RNA segments encoding PB2, PB1, PA, HA, NP and NS were related most closely to those of human viruses, whilst two of the RNA segments (NA and M) were related most closely to those of equine viruses. The HA gene was most similar to that of A/USSR/90/77 (H1N1) but amino acid differences suggested independent genetic drift. In contrast, there were relatively few changes in the NA and M genes compared to those of A/equine/Prague/1/56 (H7N7).
Url:
DOI: 10.1007/s007050050140
Affiliations:
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H." last="Brown">I. H. Brown</name><affiliation><wicri:noCountry code="subField">GB</wicri:noCountry></affiliation></author><author><name sortKey="Hill, M L" sort="Hill, M L" uniqKey="Hill M" first="M. L." last="Hill">M. L. Hill</name><affiliation><wicri:noCountry code="subField">GB</wicri:noCountry></affiliation></author><author><name sortKey="Harris, P A" sort="Harris, P A" uniqKey="Harris P" first="P. A." last="Harris">P. A. Harris</name><affiliation><wicri:noCountry code="subField">GB</wicri:noCountry></affiliation></author><author><name sortKey="Alexander, D J" sort="Alexander, D J" uniqKey="Alexander D" first="D. J." last="Alexander">D. J. Alexander</name><affiliation><wicri:noCountry code="subField">GB</wicri:noCountry></affiliation></author><author><name sortKey="Mccauley, J W" sort="Mccauley, J W" uniqKey="Mccauley J" first="J. W." last="Mccauley">J. W. Mccauley</name><affiliation><wicri:noCountry code="subField">GB</wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j">Archives of Virology</title><title level="j" type="abbrev">Arch. Virol.</title><idno type="ISSN">0304-8608</idno><idno type="eISSN">1432-8798</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Vienna</pubPlace><date type="published" when="1997-05-01">1997-05-01</date><biblScope unit="volume">142</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="1045">1045</biblScope><biblScope unit="page" to="1050">1050</biblScope></imprint><idno type="ISSN">0304-8608</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0304-8608</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Summary: An H1N7 influenza A virus, isolated from pigs in England in 1992, was examined genetically to determine the characteristics and probable origin of the eight gene segments. Six of the RNA segments encoding PB2, PB1, PA, HA, NP and NS were related most closely to those of human viruses, whilst two of the RNA segments (NA and M) were related most closely to those of equine viruses. The HA gene was most similar to that of A/USSR/90/77 (H1N1) but amino acid differences suggested independent genetic drift. In contrast, there were relatively few changes in the NA and M genes compared to those of A/equine/Prague/1/56 (H7N7).</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Alexander, D J" sort="Alexander, D J" uniqKey="Alexander D" first="D. J." last="Alexander">D. J. Alexander</name><name sortKey="Brown, I H" sort="Brown, I H" uniqKey="Brown I" first="I. H." last="Brown">I. H. Brown</name><name sortKey="Harris, P A" sort="Harris, P A" uniqKey="Harris P" first="P. A." last="Harris">P. A. Harris</name><name sortKey="Hill, M L" sort="Hill, M L" uniqKey="Hill M" first="M. L." last="Hill">M. L. Hill</name><name sortKey="Mccauley, J W" sort="Mccauley, J W" uniqKey="Mccauley J" first="J. W." last="Mccauley">J. W. Mccauley</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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